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Clinical reviews
ACTIVE FLUID DE-RESUSCITATION IN CRITICALLY ILL PATIENTS WITH SEPTIC SHOCK: A SYSTEMATIC REVIEW AND META-ANALYSIS
Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
PDF8 pages1.2 MB
The systematic review included thirteen trials with a total of 8,030 patients, focusing on the effects of active fluid de-resuscitation strategies in septic shock. The primary objective was to assess short-term mortality outcomes associated with these interventions. Results indicated that none of the randomized-controlled trials demonstrated a significant reduction in mortality, although some non-randomized trials suggested potential benefits. The review highlights the complexity and variability of de-resuscitation strategies and their implications for clinical practice.
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