anthypertensive pharmacology

Dr. Nachwera Peter; Dr. Nankunda Oreb

The presentation introduces the global burden of hypertension and its rising prevalence in Uganda, emphasizing the importance of blood pressure control to prevent cardiovascular disease. It reviews the classification of hypertension, risk factors, and the underlying physiology of blood pressure regulation. Detailed drug classes are discussed, including renin inhibitors, beta‑blockers, alpha‑blockers, and vasodilators, with emphasis on mechanisms of action, clinical indications, and special considerations such as use in pregnancy and diabetes. The lecture also highlights drug interactions, adverse effects, and therapeutic strategies for resistant hypertension.