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Amy M. VandenBerg
Major depressive disorder (MDD) is characterized by one or more major depressive episodes without a history of manic or hypomanic episodes. The chapter outlines the emotional, physical, cognitive, and psychomotor symptoms associated with MDD, as well as the diagnostic criteria from the DSM-5-TR. Treatment strategies include pharmacotherapy, psychotherapy, and monitoring for treatment efficacy and side effects. The chapter emphasizes the need for a comprehensive approach to managing MDD, including consideration of adjunctive therapies and the evaluation of therapeutic outcomes.
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