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Clinical reviews
EUGLYCEMIC DIABETIC KETOACIDOSIS IN THE ERA OF SGLT-2 INHIBITORS
Harbor-UCLA Medical Center, Inova Fairfax Hospital
PDF20236 pages631 KB
Euglycemic diabetic ketoacidosis (EDKA) is an emerging complication of diabetes linked to the increasing use of sodium-glucose transporter type 2 (SGLT-2) inhibitors. The absence of hallmark hyperglycemia complicates its diagnosis, necessitating a classification system based on serum pH and bicarbonate levels. The paper proposes a treatment algorithm that emphasizes monitoring anion gap and ketones to guide insulin and fluid management. Increased awareness and timely diagnosis of EDKA are crucial for effective management.
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