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Clinical reviews
GLP-1 RECEPTOR AGONISTS
Massachusetts Medical Society
PDF202612 pages1.2 MB
GLP-1 receptor agonists are incretin analogues that promote glucose-mediated insulin release and have multiple mechanisms of action, including reducing gastric emptying and inhibiting glucagon secretion. They have shown significant effects on blood glucose levels and body weight, as well as reducing cardiovascular risk and slowing renal failure progression in high-risk patients. The article also addresses potential adverse effects and ongoing research into additional uses for these medications.
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