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Clinical reviews
HEART–LUNG INTERACTIONS IN COMBINED DISTRIBUTIVE SHOCK AND ARDS: APPLIED CARDIOPULMONARY PHYSIOLOGY AT THE BEDSIDE
Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania; OUTCOMES RESEARCH Consortium; Department of Critical Care Medicine, Tzaneio General Hospital; Department of Cardiology, Sismanogleio General
PDF32 pages2.2 MB
Distributive shock and acute respiratory distress syndrome (ARDS) are syndromes of profound pathophysiological complexity, each independently associated with high morbidity and mortality. When coexistent, they create a state of synergistic cardiopulmonary failure where conventional, protocolized management approaches are often insufficient. The review examines the distinct hemodynamic implications of pulmonary versus extrapulmonary ARDS phenotypes and emphasizes the clinical relevance of mixed phenotypes. Advanced monitoring modalities are discussed as invaluable for detecting injurious respiratory mechanics.
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