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Hamida Hammad, Engi Ahmed, Bart N. Lambrecht
Asthma is a chronic inflammatory disease affecting millions globally, with significant mortality rates. The review focuses on type 2 high asthma, driven by Th2 cells and associated cytokines, and contrasts it with type 2 low asthma characterized by neutrophils. It discusses the development of targeted therapies based on the distinct mechanisms of asthma endotypes and highlights emerging therapeutic strategies that promise to enhance asthma management.
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