LIPID MANAGEMENT FOR THE PREVENTION OF ATHEROSCLEROTIC CARDIOVASCULAR DISEASE

Erin D. Michos, M.D., M.H.S., John W. McEvoy, M.B., B.Ch., Roger S. Blumenthal, M.D.

The article discusses the historical context of cholesterol management, beginning with the Framingham Heart Study's identification of serum cholesterol as a risk factor for coronary heart disease. It reviews the evolution of guidelines, particularly those from the American College of Cardiology and American Heart Association, and emphasizes the role of lifestyle changes and pharmacotherapy in managing lipid levels. The review also details recent clinical trials and their implications for practice, particularly regarding LDL cholesterol and cardiovascular risk reduction.