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Springer-Verlag GmbH Germany, part of Springer Nature
Critically ill patients in the intensive care unit (ICU) are at significant risk for developing stress ulcers, which can lead to gastrointestinal bleeding. The document reviews the historical and current pharmacologic approaches to stress ulcer prophylaxis (SUP), including the use of proton pump inhibitors (PPIs) and histamine-2-receptor antagonists (H2RAs). It highlights the importance of identifying patients at risk and the ongoing research aimed at optimizing SUP strategies in the ICU setting.
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