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Mayo Clinic College of Medicine and Science, Rochester, MN, USA
Lupus nephritis is a severe manifestation of systemic lupus erythematosus, and despite advances in treatment, many patients still experience relapses leading to chronic kidney disease. The authors discuss the increasing practice of protocol kidney biopsies to guide immunosuppression management, questioning the validity of this approach. They argue that immunological markers are more predictive of relapses than biopsy results, suggesting a shift in focus towards clinical and immunological monitoring.
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