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Clinical reviews
RESISTANCE TO UNFRACTIONATED HEPARIN IN THE ICU: EVALUATION AND MANAGEMENT OPTIONS
Springer-Verlag GmbH Germany, part of Springer Nature
PDF20233 pages1.3 MB
Unfractionated heparin remains a critical anticoagulant in the ICU due to its rapid action and reversibility. However, its efficacy can vary significantly among patients, leading to what is termed heparin resistance. This document evaluates the definitions of heparin resistance and suggests management strategies, including the use of alternative anticoagulants and monitoring techniques. It emphasizes the importance of individualized treatment approaches based on patient-specific factors and clinical settings.
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