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Clinical reviews
SEPSIS
Mervyn Singer, Derek C Angus, Djillali Annane, Michael Bauer, Andre C Kalil, Michael Klompas, Flavia R Machado, Greg S Martin, Adrienne G Randolph, Manu Shankar-Hari, Nathan I Shapiro, Greet Van den Berghe
PDF13 pages1.5 MB
Sepsis is a major global health concern characterized by a dysregulated immune response to infection, which can lead to severe organ dysfunction and high mortality rates. The document emphasizes the importance of early recognition and individualized treatment based on rapidly accessible biomarkers. It highlights the significant impact of sepsis on vulnerable populations, particularly children and the elderly, and discusses the evolving understanding of its pathobiology and management strategies. The aim is to unravel the complexities of sepsis and improve outcomes through better prevention and treatment approaches.
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