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Clinical reviews
SEPSIS-INDUCED DISSEMINATED INTRAVASCULAR COAGULATION: AN INTERNATIONAL ESTRANGEMENT OF DISEASE CONCEPT
Osaka Medical and Pharmaceutical University, Hokkaido University Faculty of Medicine, Kakogawa Acute Care Medical Center
PDF9 pages2.0 MB
Disseminated intravascular coagulation (DIC) is an acquired syndrome characterized by widespread intravascular activation of coagulation, which can be triggered by various insults, including sepsis. The review emphasizes the discrepancies in management approaches between Japan, where DIC is often treated as a therapeutic target, and Western countries, which rely on results from large randomized controlled trials. It also explores the potential role of machine learning in improving patient selection for treatment. The authors argue for a more nuanced understanding of DIC in the context of sepsis, advocating for tailored therapeutic strategies based on individual patient factors.
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