SEPTIC SHOCk real 2 (2)

JHO DR.MUHEREZA LIVING GODFREY, SHO DR.NIWAMANYIRE VICTOR

Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection, while septic shock involves persistent hypotension and critical reduction in tissue perfusion. The document details common causative agents, predisposing factors like diabetes and immunosuppression, and highlights the significant global and Ugandan burden of sepsis, particularly in neonates. Management includes early resuscitation, source control within 6 hours, appropriate antibiotic or antifungal therapy, and supportive measures like oxygen therapy and glucose control.