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SEPTIC SHOCK2345-1 (2)
JHO DR. MUHEREZA LIVING GODFREY; SHO DR. NIWAMANYIRE VICTOR
PPTX47 pages2.3 MB
Sepsis is defined as life‑threatening acute organ dysfunction caused by a dysregulated host response to infection, while septic shock adds persistent hypotension requiring vasopressors and elevated lactate despite adequate fluid resuscitation. The document outlines global and Ugandan epidemiology, common causative organisms, and predisposing factors such as diabetes, cirrhosis, and invasive devices. It reviews diagnostic considerations, source‑control strategies, fluid and vasopressor therapy, antimicrobial and antifungal recommendations, and adjunctive measures including awake proning and supportive care. The material is organized as a teaching deck with detailed sections on investigations, monitoring, and additional therapies.
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