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THERAPEUTIC DRUG MONITORING OF COLISTIN IN PATIENTS WITH CARBAPENEM-RESISTANT INFECTIONS AND VARYING RENAL FUNCTION: A SERIES CASE REPORT OF 5 PATIENTS
Qiuyu Zhu, MSc; Juan Wang, PhD; Fangqiong Li, MSc; Ji Shen, PhD; Xiaoting Gong, PhD; Bo Yang, MSc; Xufen Xia, MSc; Yuexing Tu, PhD
PDF8 pages1.1 MB
The report discusses the challenges of treating carbapenem-resistant gram-negative bacterial infections, particularly focusing on the use of colistin in patients with different renal function profiles. It includes detailed patient cases, interventions, and outcomes, emphasizing the need for careful monitoring of colistin plasma concentrations to optimize treatment and minimize nephrotoxicity. The findings underscore the importance of individualized dosing strategies in critically ill patients.
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