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Stanley Cohen, MD; Amy Cannella, MD, MS, RhMSUS; James R O'Dell, MD; Philip Seo, MD, MHS
The treatment of rheumatoid arthritis (RA) is aimed at controlling synovitis, preventing joint damage, maintaining musculoskeletal function, and relieving pain. Early intervention is crucial, as prolonged disease activity can lead to diminished treatment responses. This document specifically addresses the management of RA in adults who exhibit resistance to initial csDMARD therapy, detailing the necessary adjustments in treatment regimens to achieve effective disease control. It also references broader management strategies and therapies for RA.
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