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Journal of Intensive Care
Sepsis and septic shock remain a global health challenge with high mortality and long-term morbidity. Contemporary evidence highlights immune dysregulation, endothelial dysfunction, and biological heterogeneity as key factors in the management of sepsis. The document discusses the evolution of clinical management from uniform approaches to precision-guided strategies that integrate subphenotyping, biomarkers, and novel therapies. It aims to provide insights into the latest advancements and recommendations for effective sepsis treatment.
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