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Clinical reviews
USE OR MISUSE OF ALBUMIN IN CRITICAL ILL PATIENTS
Adult Transplant ICU, Organ Transplant Center of Excellence, King Faisal Specialist Hospital and Research Center; Department of General-, Visceral-, and Transplant Surgery, Medical Center University Duisburg-Essen; Department of Anesthesiology and
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Since its introduction in 1940, albumin has been widely used in clinical settings, particularly in critical care. However, a meta-analysis in 1998 raised concerns about its safety, suggesting a potential increase in mortality among patients receiving albumin. This review synthesizes findings from various studies over the past two decades to clarify which patient cohorts may benefit from albumin treatment, particularly in the ICU setting. The authors aim to provide an evidence-based perspective on the use of albumin for critically ill patients, addressing both its benefits and risks.
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