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Guidelines & protocols
WHO TB Guidelines Module 4 Treatment and care Updates in Medicine
World Health Organization
PDF2025458 pages4.9 MB
This 2025 WHO guideline outlines standardized treatment regimens for various forms of tuberculosis, emphasizing simplified delivery for Hr‑TB without separate intensive and continuation phases. It details monitoring protocols, safety precautions, and laboratory testing requirements, especially for hepatotoxicity and drug resistance. The document incorporates GRADE evidence profiles, implementation considerations, and statistical analysis plans to support clinical decision‑making. Annexes provide additional evidence tables, unpublished data summaries, and methodological details. The guideline is intended for health professionals managing TB care worldwide.
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