2023 The Bethesda Handbook of Clinical Oncology

Oncology

This handbook provides detailed information on clinical oncology, emphasizing evidence-based treatment strategies. It delves into the complexities of selecting and sequencing therapies based on patient factors, disease burden, and molecular tumor profiling. The text highlights key clinical trials like CALGB 80,405 and FIRE-3, discussing their findings on treatments for metastatic colorectal cancer and the impact of tumor sidedness. It also covers adjuvant chemotherapy recommendations, intraperitoneal therapy, and carboplatin dosing, including considerations for hypersensitivity reactions to chemotherapy agents.