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University of Chicago Medicine
Jaundice is a clinical manifestation resulting from disorders of bilirubin metabolism, hepatocellular dysfunction, or biliary obstruction. The review emphasizes the importance of a systematic evaluation to determine the underlying cause of jaundice, which can often be nonspecific. Initial evaluation begins with liver chemistry tests, and further imaging and serologic evaluations are discussed to elucidate the mechanisms of disease. The document aims to provide a framework for improving patient outcomes through a structured diagnostic approach.
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