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American College of Gastroenterology
Acute liver failure (ALF) is a life-threatening condition that occurs in patients without preexisting liver disease, leading to rapid clinical deterioration. The guidelines represent the official practice recommendations of the American College of Gastroenterology and are based on a review of scientific evidence using the Grading of Recommendations, Assessment, Development and Evaluation process. The document emphasizes the need for individualized care in specific clinical scenarios due to the variety of presentations of ALF.
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