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Clinical reviews
ADVANCES IN COMBINATION THERAPIES FOR SERIOUS INFECTIONS DUE TO MULTIDRUG-RESISTANT GRAM-NEGATIVE BACILLI
Luca Mezzadri, Abi Manesh, Ya-Ting Chang, Kim Anh Nguyen, David L. Patterson
PDF202654 pages2.1 MB
The article discusses various combination regimens for treating infections due to multidrug-resistant gram-negative bacilli, emphasizing the challenges in demonstrating the superiority of these therapies over monotherapy. It highlights the importance of selecting appropriate backbone agents based on infection type and local resistance patterns. The review also addresses the limitations of current clinical evidence and the need for further research to establish definitive treatment guidelines.
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