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Clinical notes
Infectious Mononucleosis (2)
Makerere University Department of Pathology
PPTX202122 pages2.0 MB
Infectious mononucleosis is primarily caused by Epstein‑Barr virus, with cytomegalovirus as an alternative agent. It predominantly affects adolescents and young adults, presenting with fever, sore throat, lymphadenopathy, and occasionally splenomegaly. Diagnosis relies on clinical assessment, heterophile antibody testing, and serology, while treatment is supportive with rest and analgesics. Potential complications include splenic rupture, airway obstruction, and neurologic sequelae. The disease is usually self‑limiting, but a minority of cases may develop serious complications.
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