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Peter J. Schwartz, M.D., Lia Crotti, M.D., Ph.D.
Long QT syndrome is a genetic disorder with a prevalence of approximately 1 in 2000 live births, though it may be underdiagnosed. The condition is marked by prolonged QT intervals on ECG and a tendency for dangerous arrhythmias, particularly under stress. The article reviews historical perspectives, clinical implications, and current treatment strategies, including the use of beta-blockers and ICDs. It also highlights the need for careful risk assessment and therapeutic optimization in managing affected patients.
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