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SEX DIFFERENCES IN HUMAN AND ANIMAL TOXICOLOGY: TOXICOKINETICS
Environmental and Occupational Health Sciences Institute and Consortium for Risk Evaluation with Stakeholder Participation at Rutgers—Robert Wood Johnson Medical School
PDF201739 pages589 KB
The manuscript emphasizes that sex, defined as being female or male, interacts with xenobiotic exposures and affects their toxicokinetics and outcomes. It outlines the various biological and physiological differences between sexes that can lead to different responses to environmental chemicals and pharmaceuticals. The document calls for more inclusive research designs that account for sex differences to improve understanding and management of toxic effects.
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