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Clinical reviews
TIRZEPATIDE VERSUS INTENSIFIED CONVENTIONAL CARE AFTER 2 YEARS OF TREATMENT IN EARLY TYPE 2 DIABETES
Stefano Del Prato, MD; Robert J. Heine, MD; Federico C. Pérez Manghi, MD; Stanley H. Hsia, MD; Elisa Gomez-Valderas, MS; Meltem Zeytinoglu, MD; Elisa Razzoli, MD; Jacek Kiljanski, MD; Palash Sharma, PhD; Alastair Knights, PhD; Vivian Thuyanh Thieu, PhD
PDF13 pages301 KB
The study investigates whether initiating treatment with tirzepatide, a GLP-1 receptor agonist, early in the course of type 2 diabetes can lead to better glycemic control than current treatment methods. Conducted across 78 sites in 10 countries, the trial involved 794 adults with a history of type 2 diabetes. The primary objective was to demonstrate the noninferiority of tirzepatide compared to intensified conventional care in reducing hemoglobin A1c levels over two years.
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