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Clinical reviews
ADVANCES AND UPDATES IN ANTIBIOTIC COMBINATION THERAPY
Department of Health Sciences (DISSAL), University of Genoa; Infectious Diseases Unit, Policlinic San Martino Hospital – IRCCS, Genoa, Italy
PDF54 pages725 KB
The perspective focuses on selected studies from 2018 to 2025 that investigate the efficacy of antibiotic combinations against major gram-positive and gram-negative pathogens. It challenges existing dogmas regarding combination therapy and emphasizes the need for a tailored approach based on specific clinical syndromes. The authors argue that strong indications for combination therapy exist only in particular situations, such as endocarditis and toxic shock syndrome.
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