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Clinical reviews
ATORVASTATIN, CARDIOVASCULAR EVENTS, AND DISABILITY-FREE SURVIVAL IN OLDER ADULTS
NEJM
PDF202613 pages440 KB
Conducted as a double-blind, randomized, placebo-controlled trial, this research involved community-dwelling adults aged 70 and older with no history of cardiovascular disease, diabetes, or dementia. Participants were assigned to receive either atorvastatin or a placebo, with the study focusing on major cardiovascular events and disability-free survival as primary endpoints. The findings contribute to the ongoing debate regarding statin use in older populations, particularly in terms of safety and efficacy.
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