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Clinical reviews
CATHETER-DIRECTED THROMBOLYSIS IN INTERMEDIATE-HIGH–RISK PULMONARY EMBOLISM
Department of Cardiology, Third Faculty of Medicine, Charles University, Kralovske Vinohrady Hospital, Prague, Czech Republic
PDF202611 pages273 KB
The study is a multicenter, open-label, randomized trial that assigns patients with intermediate-high-risk acute pulmonary embolism to receive either catheter-directed thrombolysis with alteplase plus anticoagulation therapy or standard anticoagulation therapy alone. The primary outcome measured is a composite of death from any cause, recurrence of pulmonary embolism, or cardiorespiratory decompensation within 7 days. The findings aim to clarify the effectiveness of thrombolysis in this patient population.
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