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Clinical reviews
COMPARATIVE EFFECTIVENESS OF ASPIRIN DOSING IN CARDIOVASCULAR DISEASE
The New England Journal of Medicine
PDF202110 pages540 KB
The research employs an open-label, pragmatic design, randomly assigning patients to receive either 81 mg or 325 mg of aspirin daily. The primary effectiveness outcome is a composite of death from any cause, hospitalization for myocardial infarction, or hospitalization for stroke, while the primary safety outcome focuses on hospitalization for major bleeding. The findings aim to clarify the optimal aspirin dosing strategy in this patient population.
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