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Oregon Clinical and Translational Research Institute, Oregon Health and Science University; Duke University School of Medicine
Diuretics are essential in managing heart failure, particularly in cases of acute decompensation and diuretic resistance. Despite their frequent use, there is a lack of robust clinical trial evidence guiding their application. This article explores the complexities of diuretic therapy, including the challenges faced by patients who are diuretic resistant and the pharmacokinetic factors influencing treatment efficacy. The authors aim to provide a comprehensive understanding of diuretic use in heart failure management.
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