Please wait while we open this resource.
K
Clinical reviews
EFFICACY AND SAFETY OF SELECTIVE ALDOSTERONE SYNTHASE INHIBITORS FOR BLOOD PRESSURE REDUCTION IN PATIENTS WITH CKD: A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS
Marieta Theodorakopoulou, Fotini Iatridi, Aikaterini Theodosiadi, Manfred Hecking, Giovanni Strippoli, Pantelis Sarafidis
PDF8 pages1.7 MB
Aldosterone synthase inhibitors (ASIs) have shown significant blood pressure lowering efficacy in patients with uncontrolled hypertension, but their effects in chronic kidney disease (CKD) remain less understood. This study includes five randomized controlled trials with a total of 1,148 patients, assessing the impact of ASIs on systolic and diastolic blood pressure, albuminuria, and hyperkalemia incidence. The findings indicate a notable reduction in blood pressure and albuminuria among CKD patients treated with ASIs, highlighting their potential role in managing hypertension in this population.
Sign in to open
Ask this resource
Answers use this document only.
Your first question is free.
More like this
Resources from the same specialty and type. Curated links will replace these when added.
Clinical Resources
Documents that extend or complement this resource.
CARDIOVASCULAR COMPLICATIONS IN CHRONIC KIDNEY DISEASE: A REVIEW FROM THE EUROPEAN RENAL AND CARDIOVASCULAR MEDICINE WORKING GROUP OF THE EUROPEAN RENAL ASSOCIATION
Same clinical topic · Nephrology
THE ASSOCIATION BETWEEN DUAL RAAS INHIBITION AND RISK OF ACUTE KIDNEY INJURY AND HYPERKALEMIA IN PATIENTS WITH DIABETIC KIDNEY DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS
Same clinical topic · Nephrology
OBESITY IN CKD: CORE CURRICULUM 2026
Same clinical topic · Nephrology
OBESITY IN CKD: CORE CURRICULUM 2026
Same clinical topic · Nephrology
ACUTE GLOMERULONEPHRITIS
Same clinical topic · Nephrology
DISEASE MODIFICATION IN LUPUS NEPHRITIS: TOWARDS A PATHOPHYSIOLOGY-BASED TREATMENT PARADIGM
Same clinical topic · Nephrology
Effects of correction rate for severe hyponatremia in the intensive care unit on patient outcomes
Same clinical topic · Nephrology
CURRENT UNDERSTANDING OF SODIUM-GLUCOSE TRANSPORTER 2 INHIBITORS IN CARDIOVASCULAR-KIDNEY-METABOLIC SYNDROME
Same clinical topic · Nephrology
A COMPREHENSIVE REVIEW OF ACUTE CARDIO-RENAL SYNDROME: NEED FOR NOVEL BIOMARKERS
Same clinical topic · Nephrology