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Clinical reviews
GLP-1 RECEPTOR AGONISTS IN KIDNEY TRANSPLANT RECIPIENTS WITH PRE-EXISTING DIABETES: A RETROSPECTIVE COHORT STUDY
Babak J Orandi, Yusi Chen, Yiting Li, Garyn T Metoyer, Krista L Lentine, Michael Weintraub, Sunjae Bae, Nicole M Ali, Bonnie E Lonze, Christine J Ren-Fielding, Holly Lofton, Akash Gujral, Dorry L Segev, Mara McAdams-DeMarco
PDF202510 pages1.3 MB
Given the cardiovascular, renal, and survival benefits of GLP-1 receptor agonists for diabetes, these agents could be effective among kidney transplant recipients. However, this population differs significantly from typical trial participants, facing longer diabetes duration, greater end-organ damage, and increased cardiovascular risk. The study utilizes a national registry linked with Medicare claims to analyze real-world data on GLP-1 receptor agonist use post-transplantation.
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