HYponatraemia IN HEART FAILURE: TIME FOR NEW SOLUTIONS?

Medical University of Warsaw, Almazov National Medical Research Centre, National Medical Research Center for Therapy and Preventive Medicine, University of Glasgow

Hyponatraemia is a common condition in heart failure, particularly in decompensated patients, and serves as a marker of advanced disease. The document outlines the mechanisms behind hyponatraemia, including poor kidney perfusion and excessive arginine vasopressin secretion. It emphasizes the importance of recognizing hyponatraemia and its causes to guide treatment strategies, which have traditionally focused on fluid restriction and diuretic therapy. The review also explores new therapeutic options, including dual vasopressin antagonists and angiotensin receptor-neprilysin inhibitors, that may offer benefits for sodium homeostasis.