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Clinical reviews
LIVER TRANSPLANTATION FOR PATIENTS WITH SEVERE ACUTE ON CHRONIC LIVER FAILURE: IT IS TIME TO CHANGE PARADIGMS
Thierry Artzner, Javier Fernandez, Rajiv Jalan
PDF3 pages1.6 MB
The paper emphasizes the high mortality rates associated with critically ill cirrhotic patients in the ICU and the potential of liver transplantation (LT) to reverse both hepatic and extra-hepatic organ failure in severe ACLF cases. It reviews the prognostic factors influencing post-transplant outcomes and the importance of timely decision-making regarding transplant eligibility. The authors argue for a paradigm shift in the management of ACLF patients, advocating for the integration of LT as a viable treatment option in critical care settings.
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