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Metabolic Diseases Research Unit, IRCCS Sacro Cuore Don Calabria Hospital, Italy
The article provides a comprehensive overview of MASLD, detailing its historical context, recent reclassifications, and the metabolic dysfunction that underpins its pathogenesis. It highlights the clinical implications of MASLD, including its association with obesity and type 2 diabetes, and reviews current treatment strategies, particularly the role of GLP-1 receptor agonists. The authors emphasize the need for a multidisciplinary approach to manage this increasingly recognized liver condition.
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