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Clinical reviews
NONSTEROIDAL MINERALOCORTICOID RECEPTOR ANTAGONIST ELICITING CARDIORENAL PROTECTION IS A NEW OPTION FOR PATIENTS WITH CHRONIC KIDNEY DISEASE
Second Affiliated Hospital of Naval Medical University, Shanghai, China; Beidaihe Rehabilitation and Recuperation Center of PLA, Qinhuangdao, China
PDF202314 pages634 KB
The article reviews the mechanisms by which nonsteroidal MRAs protect cardiorenal function, emphasizing their anti-inflammatory and antifibrotic properties. It also compares the efficacy of finerenone and esaxerenone in managing CKD and associated cardiovascular risks. The review includes insights from recent clinical trials and discusses the implications for treatment strategies in patients with CKD and type 2 diabetes mellitus.
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