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Clinical reviews
NONTYPHOIDAL SALMONELLA INVASIVE DISEASE: CHALLENGES AND SOLUTIONS
Centre for International Health, University of Otago; Malawi Liverpool Wellcome Trust Programme; Institute of Infection, Veterinary, and Ecological Sciences, University of Liverpool; Department of Pathology, Kamuzu University of Health Sciences;
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Nontyphoidal Salmonella are a leading cause of community-onset bacteremia and other serious infections in sub-Saharan African countries. The article estimates that approximately 535,000 cases of nontyphoidal Salmonella invasive disease and 77,500 deaths occurred in 2017, with a significant proportion of these cases and deaths occurring in sub-Saharan Africa. The authors discuss the challenges in managing these infections, particularly in the context of co-morbidities such as malaria and HIV, and emphasize the need for effective vaccines to prevent these diseases.
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