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Clinical reviews
OSTEOGENIC PAIN: A “NOVEL” CONCEPT BASED ON RODENT AND HUMAN STUDIES
Ricardo Plancarte, MD; Sudhir Diwan, MD; Alaa A. Abd-Elsayed, MD; Mojdeh Sarzaeim, MD, PhD; B. Carolina Hernández-Porras, MD; Juan Miguel Jimenez-Andrade, PhD
PDF202613 pages1.6 MB
The review focuses on recent preclinical studies that elucidate the neurobiology of bone pain and explore novel therapeutic avenues. It discusses the challenges of current treatments, particularly the reliance on systemic opioids, and emphasizes the need for safer alternatives. By proposing the concept of osteogenic pain, the authors aim to enhance understanding and treatment of chronic bone pain associated with various skeletal conditions.
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