Clinical reviews

SEPSIS IN END-STAGE LIVER DISEASE AND ACUTE-ON-CHRONIC LIVER FAILURE: PATHOPHYSIOLOGY, DIAGNOSTIC CHALLENGES, AND PHARMACOLOGICAL MANAGEMENT

Transplant Anesthesia and Intensive Care Unit, University of Pisa, Italy

PDF202613 pages2.2 MB

Sepsis in end-stage liver disease represents a leading cause of short-term mortality in patients experiencing acute decompensation. The clinical course is influenced by systemic inflammation and immune dysfunction associated with cirrhosis. This document provides a comprehensive review of the pathophysiology, diagnostic challenges, and pharmacological management strategies for sepsis in this patient population, highlighting the complexities of treatment and the need for tailored approaches.

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SEPSIS IN END-STAGE LIVER DISEASE AND ACUTE-ON-CHRONIC LIVER FAILURE: PATHOPHYSIOLOGY, DIAGNOSTIC CHALLENGES, AND PHARMACOLOGICAL MANAGEMENT

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SEPSIS IN END-STAGE LIVER DISEASE AND ACUTE-ON-CHRONIC LIVER FAILURE: PATHOPHYSIOLOGY, DIAGNOSTIC CHALLENGES, AND PHARMACOLOGICAL MANAGEMENT

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Clinical Resources