STATINS REVISITED: THERAPEUTIC APPLICATIONS BEYOND LIPID LOWERING?

Cardiovascular Program-ICCC, IR-Hospital de la Santa Creu i Sant Pau, IIB-SantPau, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Spain; Cardiology Hospital Clinic, IDIBAPS, Spain

The article reviews the current understanding of statins and their pleiotropic effects, including their impact on inflammation, thrombosis, and endothelial function. It references a randomized trial on statin loading before CABG and discusses the lack of clinical benefits observed in recent studies. The authors emphasize the need for further investigation into the effects of statins on various patient populations and clinical outcomes.