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Clinical reviews
THE CLINICAL UTILITY OF KINETIC GLOMERULAR FILTRATION RATE
Royal Infirmary of Edinburgh, Queen Margaret Hospital
PDF20167 pages502 KB
In acutely unwell patients, estimating glomerular filtration rate (GFR) can be challenging and often inaccurate. Kinetic GFR (kGFR) is proposed as a better estimate of immediate biomarker clearance derived from two discrete measurements. This study compares kGFR with traditional estimates, such as the Modification of Diet in Renal Disease (MDRD), in predicting acute kidney injury (AKI), renal replacement therapy (RRT), and other adverse outcomes. The findings suggest that kGFR may provide a more accurate prediction of AKI compared to MDRD.
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