THROMBOTIC AND BLEEDING COMPLICATIONS DURING ANTITHROMBOTIC TREATMENT: THE NEED FOR NEW THERAPEUTIC TARGETS

Department of Cardiovascular Medicine, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; Department of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, Rome, Italy

The focus issue addresses thrombosis and antithrombotic treatments, emphasizing the need for new therapeutic targets due to the frequent and potentially life-threatening bleeding complications associated with current antithrombotic therapies. It includes state-of-the-art reviews on the reversal of antithrombotic drugs and novel therapeutic interventions for managing patients with active bleeding or imminent threats of major bleeding. The document also explores the role of specific proteins in arterial thrombosis and their implications for treatment strategies.