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Clinical reviews
VARICELLA ZOSTER VIRUS INFECTION
Andrew N. Bubak, Charlotte Warren-Gash, Cristina Tommasi, Judith Breuer, Ravi Mahalingam, Padma Srikanth, Maria A. Nagel
PDF202618 pages3.6 MB
Varicella zoster virus (VZV) is an exclusively human alphaherpesvirus that infects over 90% of the global population. The primary infection typically results in varicella (chickenpox), after which the virus establishes lifelong latency in ganglionic neurons. Reactivation of VZV can lead to herpes zoster (shingles) and various complications, including post-herpetic neuralgia and multisystem disease. Diagnosis relies on clinical presentation, and prevention strategies include vaccination. The document also covers treatment options, including antiviral medications.
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