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Clinical reviews
VITAMIN D DEFICIENCY
Harold N Rosen, MD
PDF202529 pages600 KB
Vitamin D deficiency was originally discovered as the cause of rickets due to lack of exposure to sunshine or vitamin D-rich food. It enhances intestinal absorption of calcium and phosphate, and low levels are associated with impaired calcium absorption and increased parathyroid hormone levels, leading to excessive bone resorption. The document reviews optimal calcium and vitamin D supplementation for skeletal health, particularly in the context of osteoporosis treatment, while addressing the uncertainties surrounding optimal intake levels.
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