WHEN ORAL THERAPY CAN REPLACE INTRAVENOUS ANTIBIOTICS—CHANGING PRACTICE AS NEW DATA EMERGE

Los Angeles County and University of Southern California (LAC+USC) Medical Center

The article presents a perspective on the shift from intravenous to oral antibiotic therapy, particularly for infections such as bacteremia and osteomyelitis. It highlights the importance of re-evaluating established practices in light of new evidence from randomized clinical trials. The authors argue that oral therapy is not only as effective but also more patient-centered, allowing for quicker recovery and less invasive treatment options. This change is framed as a necessary evolution in infectious disease management.