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Clinical reviews
WILL SGLT2 INHIBITORS BE EFFECTIVE AND SAFE IN PATIENTS WITH SEVERE CKD, DIALYSIS, OR KIDNEY TRANSPLANTATION
University Medical Center Groningen, University of Groningen
PDF6 pages971 KB
The clinical benefits of sodium glucose co-transporter 2 (SGLT2) inhibitors in patients with chronic kidney disease (CKD) have been well established through major clinical outcome trials. Secondary analyses from these trials suggest consistent benefits across various subgroups, including those with severe CKD and kidney transplant recipients. However, the document emphasizes the necessity for more research to ascertain the safety and efficacy of SGLT2 inhibitors in these specific populations, particularly concerning the risk of urinary tract infections and other side effects.
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