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Clinical reviews
EFFICIENCY OF HYPERTONIC SALINE IN THE MANAGEMENT OF DECOMPENSATED HEART FAILURE: A SYSTEMATIC REVIEW AND META‑ANALYSIS OF CLINICAL STUDIES
Grigore T. Popa University of Medicine and Pharmacy, Iasi, Romania; Koc University School of Medicine, Istanbul, Turkey; Cardiovascular Diseases Institute, Iasi, Romania; Suleyman Demirel University School of Medicine, Isparta, Turkey
PDF202017 pages2.3 MB
Acute decompensated heart failure (ADHF) presents significant morbidity and mortality challenges despite advancements in therapy. This review synthesizes data from 14 studies involving 3398 patients to analyze the effectiveness of hypertonic saline solution (HSS) in combination with furosemide. The findings suggest that this combination therapy may improve kidney function, diuresis, and overall patient outcomes compared to furosemide alone.
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